Skipped Doses

I’m struggling these last couple days. I kind of knew it would happen, but was hoping it wouldn’t. I’m now sitting in that uncomfortable place of just existing and randomly bursting into tears and just a splash of irritability. Ugh, I know better than to skip my nightly dose of Duloxetine (antidepressant). At least this time around it was for a good reason…well, sort of.

I only take it at night because it makes me drowsy and I already struggle with fatigue. I’ve noticed more and more lately, that when I take it any later than 7pm, I have a more difficult time waking up in the morning. On Sunday night, I accidentally missed my dose, but I woke up on time and got the kids ready and to school on time. Monday night and Tuesday morning, the same thing. Tuesday night, I took my dose late in the evening and Wednesday I slept through 10 alarms making the kids late for school. I do not want to be the reason that my kids have an excessive amount of tardiness at school, so Wednesday and Thursday, when I lost track of time and missed my 7:00pm dose, I skipped it altogether. I’m paying for it now, but at least the kids made it to school on time.

I am hopeful that next week will go much smoother and I will have my sh*t together. In the meantime, I’m so glad the weekend is here.

Thanks for letting me vent. I hope you all have a great weekend.

With love,


18 thoughts on “Skipped Doses

    1. I’ve been taking this same medication for years, and as much as I hate having to take it in the first place, I’m afraid to change it. It’s what I’m familiar with, if that makes sense? Lol.
      I do see the physician who manages it next week, so I will see what she thinks. Thank you for your suggestion. 💖


  1. I’ve used at least six different anti-depressants and each has its own interesting side effect. Effexor was the worst because, if you miss a dose, you get the “brain zaps”. I cannot describe them to anyone but an Effexor-user. I understand your reluctance to switch to something else. If it’s only a little bit broke, don’t fix it, right?

    Liked by 1 person

    1. Oh wow! I’ve never tried Effexor, but that doesn’t sound like fun at all. Exactly! I least know how this one behaves. I do think it at the very least needs adjusted maybe. May I ask, what has worked best for you?

      Liked by 1 person

      1. Well… I’ve got two issues: Severe Chronic Depression and bipolar disorder. I’ve never found a treatment for the depression that works all that well without squashing my personality. I take Depakote for the bipolar.

        So, to answer, I cope as best I can. One side of my family is American Indian, so my dad and siblings all ended up with it. I don’t think any of us ever found anything that worked…

        Liked by 1 person

      2. I’m sorry that you haven’t been able to find something that works well for the depression. Depression already steals so much from us, so I understand not wanting to take a medication that steals away from personality as well. I’m sorry that your family suffers from these as well. Sending hugs to you. Keep fighting.

        Liked by 1 person

  2. So, I’m in agreement with those suggestions to talk to dr about this. Our bodies change over time (don’t I know it! ) and it might be time to change your meds, too. Just make sure someone is around/available to watch your reaction to it the first few times. Xoxo Mom

    Liked by 1 person

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